Find out what experimental trials, like the pro-urokinase study, it participates in.
From the time.com
Like urokinase, MMPs have helpful roles, depending on the location and circumstances in the body.
From the sciencedaily.com
Recombinant pro-urokinase, like TPA, increases the chances of dangerous bleeding in the brain.
From the time.com
Enter an experimental drug called recombinant pro-urokinase.
From the time.com
Urokinase also activates a substance in blood vessels called plasminogen and turns it into plasmin, another protein-destroying enzyme.
From the sciencedaily.com
If morphine is supplied to these cells the protein urokinase is released, which the cancer cells can use to enhance their capacity to spread.
From the sciencedaily.com
The Company's commercialization efforts are currently focused on its product, urokinase for the treatment of acute massive pulmonary embolism.
From the foxbusiness.com
They show that deficiency of the enzymes urokinase-type PA and matrix metalloprotease prevented cardiac rupture after acute myocardial infarction.
From the nature.com
In a mouse study, Dickek and his team transplanted bone marrow containing macrophages that overproduce a protein-digesting enzyme known as urokinase into aged, atherosclerotic mice.
From the sciencedaily.com
The researchers also observed that the increase in urokinase upped the activity of other protein-digesting enzymes that can eat away at the structural proteins that hold a plaque together.
From the sciencedaily.com
Their data suggests that high levels of urokinase in plaque, leading to increases in plasminogen activation, may be causally related to plaque rupture and major cardiovascular events.
From the sciencedaily.com
To address this problem, the scientists coated islet cells with a special polymer film containing heparin, an anticoagulant, or urokinase, a medication that dissolves blood clots.
From the sciencedaily.com
More examples
Plasminogen activator: protease produced in the kidney that converts plasminogen to plasmin and so initiates fibrinolysis
Urokinase (trade name Abbokinase), also called urokinase-type plasminogen activator (uPA), is a serine protease . Urokinase was originally isolated from human urine, but is present in several physiological locations, such as blood stream and the extracellular matrix. ...
A drug that dissolves blood clots or prevents them from forming.
A kidney enzyme found in urine used to dissolve blood clots.
Intravenous thrombolytic agent used to restore patency to central venous catheters