Intermolecular transmission of superoxide dismutase 1 misfolding in living cells.
From the nature.com
In a hyperglycemic environment, mitochondria are cells'biggest source of superoxide.
From the sciencedaily.com
This superoxide is a pressure-sensitive explosive that will detonate when scratched.
From the en.wikipedia.org
Superoxide dismutase-1 mutations decrease protein stability and promote aggregation.
From the nature.com
The superoxide dismutase 1 enzyme, or SOD1, is present in all organisms.
From the nature.com
First, it directly reduces concentrations of superoxide, a powerful ROS.
From the sciencedaily.com
Ascorbate free radical reacts poorly with oxygen, and thus will not create a superoxide.
From the en.wikipedia.org
Simvastatin induces JNK activation downstream of Rho GTPases and superoxide production.
From the nature.com
Evidence for increased activity of the superoxide-producing enzyme.
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More examples
A metallic oxide containing the univalent anion O2-
A superoxide, also known by the obsolete name hyperoxide, is a compound that contains the superoxide anion with the chemical formula Ou2212n2. The systematic name of the anion is dioxide(1u2212). The reactive oxygen species superoxide is particularly important as the product of the one-electron reduction of dioxygen O2, which occurs widely in nature...
Term used interchangeably for the superoxide anion or the weak acid HO2(.).A very active oxygen species, it can cause substantial damage and may be responsible for the inactivation of plasma antiproteases that contributes to the pathogenesis of emphysema.
Dismutase has been found in almost all organisms living in the presence of oxygen, including some anaerobic bacteria, supporting the notion that superoxide is a key and general component of oxidative stress.
A free radical produced in mitochondria as a result of electron leakage from the electron transport chain. It can damage biological molecules such as proteins and nucleic acids.
A destructive reactive oxygen species produced as a byproduct of some oxidation reactions.