Lidocaine administered by pump and mexiletine provided the best relief.
From the sciencedaily.com
The team found no adverse effects of mexiletine, including no effects on normal cardiac rhythms.
From the sciencedaily.com
Each participant received either placebo, or 150 or 200 milligrams of mexiletine three times a day, for seven weeks.
From the sciencedaily.com
Mexiletine works through the sodium channel, which is functioning normally, to decrease muscle irritability.
From the sciencedaily.com
The team found that mexiletine at three daily doses of either 150 or 200 milligrams per dose does a great deal to alleviate myotonia.
From the sciencedaily.com
Mexiletine acts to help the muscle compensate for the ion channel abnormality that is at the core of the myotonia in this disease.
From the sciencedaily.com
The new research findings on the effectiveness of mexiletine come amid several exciting research finds by Moxley's colleagues.
From the sciencedaily.com
The researchers found that mexiletine was associated with significantly improved stiffness as reported on the IVR diary in both treatment periods.
From the sciencedaily.com
In the trial of mexiletine, evaluators measured the amount of time it took patients to relax their grip after squeezing the handles of a computerized device that measures force.
From the sciencedaily.com
More examples
Antiarrhythmic drug (trade name Mexitil) used to treat ventricular arrhythmias
Mexiletine (INN, sold under the trade name Mexitil) belongs to the Class IB anti-arrhythmic group of medicines. It is used to treat arrhythmias within the heart - or seriously irregular heartbeats. It slows nerve impulses in the heart and makes the heart tissue less sensitive. ...
Approved for the treatment of heart rhythm disorders. Being studied as a treatment for HIV-related neuropathy. Side effects can be GI distress and dizziness.