Any given word's tone contours may change depending on discursive factors such as whether the sentence is affirmative, interrogative, or imperative.
From the en.wikipedia.org
Appending interrogative or exclamative particles to a sentence turns a statement into a question or shows the attitudes of the speaker.
From the en.wikipedia.org
In a normal question, you replace the subject phrase or object phrase with a corresponding interrogative pronoun, then move it to the beginning of the sentence, like an inversion.