So all one can do is laugh about the insolubility of the problems.
From the denverpost.com
Until recently, this has proved extremely difficult owing to the inherent insolubility of lamin proteins.
From the nature.com
Cigarette smoke exposure induces CFTR internalization and insolubility, leading to airway surface liquid dehydration.
From the sciencedaily.com
Due to their insolubility in water and relative chemical inertness, pure plastics generally have low toxicity.
From the en.wikipedia.org
This disagreement, however, does not reflect any peculiarity of philosophers, so much as the insolubility of many ethical problems.
From the newscientist.com
Another common macromolecular property that does not characterize smaller molecules is their relative insolubility in water and similar solvents.
From the en.wikipedia.org
In my arguments about the insolubility of the problem of God I had never foreseen the possibility of that, of a real contact, person to person, here below, between a human being and God.
From the washingtonpost.com
The lack of any obvious enzymatic activity combined with their insolubility and filament-forming properties suggested that they are primarily structural proteins.
From the nature.com
Collagen's insolubility was a barrier to the study of monomeric collagen until it was found that tropocollagen from young animals can be extracted because it is not yet fully crosslinked.
From the en.wikipedia.org
More examples
Unsolvability: the property (of a problem or difficulty) that makes it impossible to solve
The quality of being insoluble and difficult to dissolve in liquid
(insoluble) (of a substance) incapable of being dissolved
(insoluble) admitting of no solution or explanation; "an insoluble doubt"
Solubility is the property of a solid, liquid, or gaseous chemical substance called solute to dissolve in a liquid solvent to form a homogeneous solution of the solute in the solvent. The solubility of a substance fundamentally depends on the used solvent as well as on temperature and pressure. ...
(insoluble) that cannot be dissolved; that cannot be solved; insolvable; that cannot be explained; mysterious or inexplicable
(Insoluble) Fibers that mostly do not dissolve in water and are not digested by bacteria. Examples of insoluble fibers are cellulose, lignans and some of the hemicelluloses.
(Insoluble) Substances which are impossible to dissolve/mix.