It should be noted that smaller dissociation constant indicates more efficacy.
From the en.wikipedia.org
The dissociation constant was obtained by nonlinear fitting of the responses to a steady-state algorithm using Octet software.
From the nature.com
Remarkably, we did not find a great influence of the reactions that involve gal4pd, the exception being the dissociation constant of the gal80pd to the gal4pd-DNA complex.