Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate.
From the nature.com
The Company has already established a proof-of-concept with doxorubicin, a cytotoxic drug, and shown its efficient delivery in animal solid tumor models.
From the foxbusiness.com
The second important implication of this study is that it proves the concept that linking a monoclonal antibody to a cytotoxic drug leads to an anticancer effect.
From the sciencedaily.com
ThermoDox, a heat-sensitive liposomal encapsulation of the cytotoxic cancer drug doxorubicin, may allow the deposition of much higher doses of doxorubicin than could be given systemically.
From the nature.com
They found that the drug was cytotoxic to tumor-associated endothelial cells and suppressed cell proliferation and migration without apparent toxic effects to normal tissues.
From the sciencedaily.com
A drug that damages a cell in order to kill it is called cytotoxic.
From the us.cnn.com
A second drug is then injected, which reacts with the enzyme to produce a cytotoxic compound that is concentrated in the cancer cells.
From the newscientist.com
Furthermore, cell-based assays have the advantage over cell-free assays of eliminating cytotoxic, membrane-impermeable, or intracellularly inactivate agents from a large library of drug candidates.