However, in people with CF, the gene that codes for the CFTR protein is mutated.
From the sciencedaily.com
This suggests that 50 percent of normal CFTR activity is sufficient for health.
From the sciencedaily.com
Another 33% have one F508del mutations and one other mutation of the CFTR gene.
From the forbes.com
Cystic fibrosis is known to be caused by a specific mutation on the CFTR gene.
From the sciencedaily.com
To cause disease, any changes must reduce or alter how the CFTR protein works.
From the sciencedaily.com
Human mutations in the CFTR gene might be selected for as a way to survive cholera.
From the en.wikipedia.org
They found that when the CFTR gene was intact, the sodium channel was kept in check.
From the sciencedaily.com
In other diseases, CFTR channels are overactive, which also causes problems.
From the sciencedaily.com
They chose a small region of the mammalian genome, called the CFTR region, for study.
From the sciencedaily.com
More examples
Cystic fibrosis transport regulator: the gene that is mutated in cystic fibrosis
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