Based on these findings, the researchers speculate that this basophil maturation could promote allergic reactions at multiple tissue sites.
From the sciencedaily.com
It blocks IgE from binding to the surface, and potential activation, of basophil cells, which might prevent basophils from promoting kidney inflammation.
From the sciencedaily.com
Obviously, whether omalizumab treatment or other strategies to reduce basophil activation in lupus will prove efficacious remains to be seen.
From the sciencedaily.com
When beneficial gut bacteria are altered with antibiotic-treatment, B cells release more IgE, which act on bone marrow basophil precursors and promote their development.
From the nature.com
They will also attempt to determine whether or not depleting or inactivating the basophil population might reduce the production of self-reactive antibodies that can lead to kidney damage in SLE.
From the sciencedaily.com
Signals derived from the commensal bacteria were found to act via IgE to control the number of circulating basophils by limiting the proliferation of basophil precursor cells in the bone marrow.
From the sciencedaily.com
More examples
A leukocyte with basophilic granules easily stained by basic stains
Basophil granulocytes, sometimes referred to as basophils, are the least common of the granulocytes, representing about 0.01% to 0.3% of circulating white blood cells.
(basophils) white blood cells that contribute to allergic inflammatory reactions.
(Basophils) 0.1-1.0% of total WBC; involved in allergic reactions and immune response; release histamine to enhance the body's reaction to an allergen
(Basophils) A type of white blood cell that contain granules filled with chemicals toxic to other cells and used to destroy invading bacteria and other pathogens. They belong to a group of leukocytes known as granular leukocytes or granulocytes. ...
(Basophils) have a multi-lobed nucleus and have many dark blue granules (which contain histamine) in their cytoplasm. Only about 1% of WBCs are basophils. A slight elevation in number may be seen during an allergic response, ulcerative colitis, chronic sinusitis, chicken pox and immunisations. ...
An immune system cell that attaches to antibodies and circulates throughout the blood.
A polymorphonuclear leukocyte., whose basophils granules contain heparin, histamine and other vasoactive amines. Within tissues, these cells are known as mast cells q.v.
Type of white blood cell that contains and releases histamine from intracellular granules; a type of granulocyte involved in allergic reactions; normal value: 0.5-2% or 25-100 per microliter.