Adrenal maturation, termed adrenarche, typically precedes gonadarche in mid-childhood.
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However, there are three clinical issues related to premature adrenarche.
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Premature adrenarche is the most common cause of premature pubarche.
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Adrenarche is the result of the development of a new zone of the adrenal cortex, the zona reticularis.
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An initiator of adrenarche has not yet been identified.
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Gonadarche should be contrasted with adrenarche.
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As mentioned above, premature adrenarche occurs more often in children with intrauterine growth retardation and in overweight children.
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Adrenarche is proposed as the endocrine mechanism underlying the reorganisation of insecure attachment in middle childhood.
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During adrenarche the adrenal cortex secretes increased levels of androgens such as DHEA and DHEAS, but without increased cortisol levels.
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More examples
The increase in activity of the adrenal glands just before puberty
Adrenarche is an early sexual maturation stage in some higher primates that in humans typically occurs at around 6 to 8 years of age. During adrenarche the adrenal cortex secretes increased levels of androgens such as DHEA and DHEAS, but without increased cortisol levels. ...
Onset of pubic and axillary hair; normally occurs after age 8 years.
Refers to a stage of maturation of the cortex of the human adrenal glands. It typically occurs between ages 6 and 10 years and involves both structural and functional changes. Adrenarche is a process related to puberty but distinct from hypothalamic-pituitary-gonadal maturation and function.